大

quite a chore; not that easy; fairly difficult

swelling; enlargement; becoming fat

Medicine

hypertrophy

Adjectival nouns or quasi-adjectives (keiyodoshi); Nouns which may take the genitive case particle 'no'

maximum

Mathematics

local maximum

Noun or participle which takes the aux. verb suru

(large) compilation

culmination (of hard work)

(and) many others; extras (in a film)

infinity

with religious zeal; with utmost devotion; take great care of

exceptionally large

extra-large

school inter-class ball-game competition

New World (esp. the Americas, but also Australasia)

excessive; too much; unreasonable

fist-sized

maximum value

world war

Minister for Foreign Affairs

greatest ... in history

biggest; largest scale

taikō (esp. Toyotomi Hideyoshi); title for a regent, later for the grand chancellor, also for the father of an Imperial adviser (advisor) who passed the role to his son

Abbreviation

medical university; medical college; medical school

Buddhism

the five elements (in Japanese philosophy: earth, water, fire, wind and void)

Abbreviation; Buddhism

five great wisdom kings

Abbreviation

college of the arts; university of the arts; art university

exaggerated; extravagant; overdone

Abbreviation

women's college; women's university